Symptoms & causes

Reading your symptoms, and finding the cause

Almost everything useful about neuropathy comes from the pattern rather than the sensation. Where it started, whether both sides match, and how fast it moved will tell a clinician more than any description of how it feels.

A seated person holding one bare foot in both hands, paying attention to the sensation

The four questions that do most of the work. Where did it start? Did both sides begin together? How quickly has it moved? And what does it actually feel like — burning, numb, electric, or like walking on cotton? Bring those four answers to an appointment and you have done most of the useful thinking already.

What peripheral neuropathy means

Damage to the nerves outside the brain and spinal cord. It is a description of what has happened rather than a disease in itself, in the same way that “fracture” describes a broken bone without saying how it broke.

It reaches the feet first because the nerves running to your toes are the longest in the body and the hardest to maintain at their far end. That single fact explains the classic progression — toes, then the ball of the foot, then upward, on both sides at once — and it is why a problem in one foot only, or one that started higher up, usually points somewhere else entirely. The full explanation is here.

Reading your own pattern

01
Where did it start, and where is it now?
Toes first, spreading slowly upward, is the length-dependent pattern that points at a systemic cause. Starting in one patch, or higher up the leg, does not.
02
Both sides, or one?
Symmetric suggests something acting on the whole nervous system — glucose, a deficiency, a toxin. One-sided suggests a nerve compressed at a single point, or a nerve root in the back.
03
How fast?
Years is typical. Weeks is not, and rapid progression deserves prompt assessment rather than a wait-and-see.
04
What kind of sensation?
Burning, stabbing and temperature confusion are small-fiber symptoms. Numbness, unsteadiness and a walking-on-cotton feeling are large-fiber. Most people have a mixture, and the mixture shifts over time.

Symptom guides

Numb toes and numb feet

Where the numbness sits, whether both sides match, and how fast it arrived narrow the cause more than the sensation does.

Read the guide

Burning feet at night

Why the evening is reliably worse, and why the two things people try first — a heating pad and an ice bath — are the two most likely to injure a numb foot.

Read the guide

Tingling in feet

Pins and needles that will not settle, what separates a positional tingle from a persistent one, and when it needs testing.

Read the guide

Peripheral neuropathy symptoms

The full symptom picture across small, large and autonomic fibers, and which combination points where.

Read the guide

Foot drop

When the front of the foot stops lifting. Some causes recover if they are found early, which is why this one is urgent.

Read the guide

Autonomic symptoms

Dizziness on standing, feet that no longer sweat, digestive change — nerve symptoms that do not look like nerve symptoms.

Read the guide

Causes and conditions

The list of causes is long; the practical version is short. Find out whether yours is one of the correctable ones — because that is where real improvement comes from, and because a search that stopped at “probably age” is an unfinished search.

Neuropathy in the feet

The foundation page: what the damage is, why it starts in the toes, the causes worth ruling out, and whether it can be reversed.

Start here

Diabetic neuropathy

The four patterns diabetes produces, only one of which is the numb feet everyone pictures.

Read the guide

Small fiber neuropathy

Why the nerve test comes back normal while your feet burn, and how it is actually diagnosed.

Read the guide

Types of neuropathy

Mononeuropathy, polyneuropathy, autonomic and more — the vocabulary clinicians use and what each implies.

Read the guide

Alcohol-related neuropathy

Directly toxic to nerves and it blocks the B vitamins nerves need — damage by two routes at once.

Read the guide

Radiculopathy vs neuropathy

A pinched nerve root in the back and a length-dependent polyneuropathy feel similar and are managed completely differently.

Read the guide

Tarsal tunnel syndrome

The tibial nerve squeezed behind the inner ankle burns the sole of one foot — a findable, sometimes fixable cause.

Read the guide

Baxter’s neuropathy

A trapped nerve in the heel that is routinely mistaken for plantar fasciitis that will not heal.

Read the guide

Why the cause matters more than the label

Several common causes are correctable, and correcting them early is the only route to genuine recovery: vitamin B12 deficiency, thyroid disease, alcohol, and an excess of vitamin B6 — which appears at high doses in many “nerve support” supplements and causes the very problem they are bought for. Diabetes and prediabetes are the largest single group, and glucose control is the intervention with the strongest evidence for slowing progression.

The tests worth asking for by name are glucose and A1c, vitamin B12, thyroid function, kidney function and a blood count. Questions worth asking at the appointment are here.

Describing it usefully

They want to knowSay something like
Where it started and where it is now“Both big toes about two years ago, now up to the ball of both feet.”
Whether the two sides match“Both feet, about the same.” Or: “The left is much worse.”
How fast it has moved“Slowly over years” and “noticeably worse in the last six weeks” point at different things entirely.
What it feels likeBurning, electric, pins and needles, numb, or like walking on cotton.
What changes itWorse at night, better when walking, worse after standing all day. Nerve pain is characteristically worse at rest.

Get seen promptly for numbness that is spreading noticeably, new weakness — especially difficulty lifting the front of the foot — a new difference between the two sides, any open sore or blister, or a foot that has become warm, swollen and changed shape without an injury. A rough week is not the same as a change in pattern.

Common questions

Is neuropathy always diabetes?

No. Diabetes is the most common single cause, but a meaningful share of cases come from something else and several of those are correctable. If nobody has checked your B12, thyroid and glucose tolerance, the search is not finished.

My nerve test was normal but my feet burn. What now?

Standard nerve conduction studies measure large fibers. Burning is a small-fiber symptom and small-fiber neuropathy is routinely present with a completely normal study. It needs a different test.

Why is it always worse at night?

Less competing sensation, less distraction, and you are lying still. It is one of the most consistent features of nerve pain and it does not mean the condition is deteriorating.

Does numbness without pain still matter?

More, not less. Painless numbness carries the same risk of unnoticed injury while removing the symptom that would otherwise send you to a clinician. That is what the daily foot check is for.

For our Michigan neighbors

Has the pattern
actually been examined?

Protective sensation, pinprick, vibration and circulation can all be tested in one visit. Dr. Biernacki’s practice in Howell and Bloomfield Township does this every week.

Explore Michigan appointments →

Everywhere else, take this page to your own clinician.